Department of Aeronautics and Astronautics Feedforward Control of the Magnetic Ball
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Ionizing radiation induces ferroptosis in splenic lymphocytes of mice
Backgrounds: It remains unclear whether radiation-induced haemorrhage in the spleen causes iron accumulation, and subsequently, ferroptosis in splenic lymphocytes. In this study, we investigated the occurrence of ferroptosis in splenic lymphocytes of gamma-irradiated mice. Materials and Methods: Mice were subjected to gamma radiation from a 137Cs source. Iron, Ferroportin 1, and iron regulatory...
متن کاملDevelopment of methemoglobin-based biological dosimetry in gamma–irradiated mice
Background: A new biological dosimeter based on methemoglobin level was developed in this study. Materials and Methods: Methemoglobin level in erythrocytes from mice subjected to &gamma rays from a 60Co source was detected using the methemoglobin kit. The dose range was from 0.5 to 8 Gy and the dose rate was 0.5 Gy/min. Results: The results demonstrate that methemoglobin level increases with in...
متن کاملRadiosensitizing effect of deferoxamine on human glioma cells
ABSTRACT Background: Tumor cells exhibit an increased requirement for iron to support their rapid proliferation. Deferoxamine (DFO), an iron chelator, has been reported to have anti-proliferative effects on cancer cells through induction of apoptosis and cell cycle arrest. X-rays also induce apoptosis and cell cycle arrest. However, limited information is available regarding the effect of iron...
متن کاملClustering of nasopharyngeal carcinoma intensity modulated radiation therapy plans based on k-means algorithm and geometrical features
Background: The design of intensity modulated radiation therapy (IMRT) plans is difficult and time-consuming. The retrieval of similar IMRT plans from the IMRT plan dataset can effectively improve the quality and efficiency of IMRT plans and automate the design of IMRT planning. However, the large IMRT plans datasets will bring inefficient retrieval result. Materials and Methods: An intensity-m...
متن کاملImpacts of multiple-field irradiation and boron concentration on the treatment of boron neutron capture therapy for non-small cell lung cancer
Background: Boron neutron capture therapy (BNCT) is a radiotherapy that combines biological targeting and high linear energy transfer. A potential therapeutic approach for non-small cell lung cancer (NSCLC) is considered. However, dose in lung tumor is not homogeneous, and it will reduce the effect of BNCT treatment. In order to improve the dose distribution of BNCT, the multi-field irradiation...
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